Glucophage 1000mg Tablet | Spain
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Glucophage 1000mg Tablet | Spain

Generic: Metformin Hydrochloride

Type: Tablet

Pack Size: 15 Pcs

Reduces liver glucose production: Decreases the amount of glucose produced by the liver.

Enhances insulin sensitivity: Improves the body's response to insulin, facilitating better glucose uptake by cells.

Lowers intestinal glucose absorption: Reduces the amount of glucose absorbed from the digestive tract.

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MRP: ৳ 520 2% Off

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✅ Description:

Glucophage 1000 is prescribed for managing type 2 diabetes mellitus, especially in overweight individuals when dietary changes and exercise alone do not provide adequate blood sugar control.

  • Adults: Can be used alone or with other oral antidiabetic medications or insulin.
  • Children (10 years and older) & Adolescents: Can be used alone or with insulin.
  • Studies have shown a reduction in diabetes-related complications in overweight adults when metformin is used as a first-line treatment after diet failure.
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✔️ How does Glucophage 1000 work?

Metformin belongs to the biguanide class of oral antihyperglycemic agents, which help regulate blood glucose without causing hypoglycemia. It works by:

✔ Reducing liver glucose production
✔ Lowering glucose absorption in the intestines
✔ Enhancing insulin sensitivity and glucose uptake in peripheral tissues

✔️ Dosage & Administration of Glucophage 1000

Metformin dosage should be tailored to individual tolerance and effectiveness without exceeding the recommended daily maximum.

Immediate-Release Tablets:

  • Adults: Start with 500 mg twice daily or 850 mg once daily with meals. Dosage can be increased in 500 mg weekly increments or 850 mg every two weeks up to a maximum of 2550 mg per day (divided doses).
  • Children (10+ years): Start with 500 mg twice daily with meals, increasing weekly by 500 mg up to 2000 mg per day (divided doses).

Extended-Release Tablets:

  • Adults: Start with 500 mg once daily with the evening meal. Dosage can be increased weekly by 500 mg up to a maximum of 2000 mg once daily or 1000 mg twice daily.
  • Children: Not studied for extended-release tablets.
  • Renal Impairment: Not recommended for patients with eGFR below 30 mL/min/1.73 m². Caution is advised if eGFR falls below 45 mL/min/1.73 m².


👴 Elderly: Metformin dosage should be adjusted based on kidney function, which declines with age. Regular kidney function assessments are advised.
👶 Children (10-12 years): Caution is advised due to limited data.
💧 Renal Function:

  • Normal kidneys: Monitor at least once a year.
  • Borderline function (elderly, lower normal GFR): Monitor 2-4 times yearly.
  • eGFR <30 mL/min: Glucophage 1000 is contraindicated.

Swallow extended-release tablets whole; do not crush, cut, or chew.

✔️ Drug Interactions:
  • Furosemide: No chronic interaction data is available.
  • Nifedipine: May enhance Glucophage 1000 absorption.
  • Cationic Drugs (e.g., Digoxin, Vancomycin, Quinidine): May compete for renal clearance, potentially affecting Glucophage 1000 levels.
  • Drugs that cause hyperglycemia (e.g., corticosteroids, diuretics, estrogens, phenytoin, thyroid hormones, calcium channel blockers): May reduce Glucophage 1000’s effectiveness.
✔️ Side Effects of Glucophage 1000

🩸 Blood Disorders: Rare cases of hemolytic anemia.
💊 Metabolism Issues: Rare cases of lactic acidosis and vitamin B12 deficiency (potential cause of peripheral neuropathy).
🤢 Gastrointestinal Issues: Common side effects include nausea, vomiting, diarrhea, abdominal pain, and appetite loss (mostly at treatment initiation). Taking Glucophage 1000 with food and slowly increasing the dose can improve tolerance.
🧠 Nervous System: Commonly causes taste disturbances.
⚠️ Liver Disorders: Rare instances of liver function abnormalities or hepatitis, reversible upon discontinuation.
🩹 Skin Reactions: Rare cases of rash, itching, and hives.

✔️ Use During Pregnancy & Breastfeeding:

🤰 Pregnancy: Uncontrolled diabetes increases the risk of birth defects and perinatal mortality. Insulin is preferred over Glucophage 1000 during pregnancy.
🤱 Breastfeeding: Metformin is excreted in breast milk. Though no adverse effects have been observed in breastfed infants, use during lactation is not recommended unless the benefits outweigh the risks.

✔️ Overdose Effects:
  • Hypoglycemia is unlikely, even at doses up to 85 grams.
  • Lactic acidosis is the primary risk and requires immediate hospitalization.
  • Hemodialysis is the most effective way to remove excess lactate and Glucophage 1000 from the system.
✔️ Precautions & Warnings:
  • Renal function monitoring is essential, as impaired kidney function increases the risk of metformin accumulation and lactic acidosis.
  • Vitamin B12 levels should be checked regularly, as long-term use may lead to deficiency.
  • Glucophage 1000 should be discontinued 2-3 days before surgery or certain diagnostic procedures (e.g., intravenous contrast imaging) and restarted only after kidney function is reassessed.
  • Avoid dehydration and severe infections, as they may increase the risk of lactic acidosis.
✔️ Storage Conditions:
  • Store below 30°C, away from light and moisture.
  • Keep out of reach of children.
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+ Q. What is the delivery time?

Delivery typically takes 1-2 business days, depending on your location.

+ Q. Does ePharma deliver internationally?

Currently, ePharma only delivers within Bangladesh.

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+ Q. What payment methods are accepted?

We accept debit/credit cards, Bkash, Nagad, and cash on delivery.

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Check our pricing section for Glucophage 1000mg Tablet | Spain price in Bangladesh. After Submitting Order, You may receive phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:
Product Availability & Pricing Notice Please note that pricing, availability, and service offerings are subject to change due to: Market fluctuations, Manufacturer or supplier adjustments, Product discontinuation or temporary unavailability, Advertising errors. All orders depend on stock availability and staff resources. If services are provided on a time-and-materials basis, any shared estimates are for planning purposes only.

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